Attention has frequently been called to the analysis of burn patient about the damage to the liver. Information concerning damage to the liver in patients with severe burns has been based on use of liver function tests and histological studies of postmortem material.
But, the articles about the changes of liver function tests in burns are rare, so we selected 50 cases of burn patients who were treated at the department of the plastic surgery for 2 weeks or more, from April 1979 to March 1981 and has no evidence of liver disease.
Total protein, level of albumin and globulin, A/G ratio, serumbilirubin and serum enzymes such as alkaline phosphatase, SGOT and SGPT for liver function were reviewed in burn patients.
The result were as folows;
1. The level of serum albumin and globuln decreased most markedly on 5 th day of burn, which was related to the burn surface. The change of globulin was small than albumin.
2. The level of serum bilirubin increased on 1st day of burn in 8 cases (37.5%) of group I and 6 cases (33%) of group II, which was related to the burn surface and depth.
3. Serum enzyme
ⅰ. Alkaline phosphatase increased most markedly on 5 th day of burn, which was realted to the burn surface and depth.
ⅱ. Transaminase increased most markedly between the 5th and 10th day of burn. In the group Ⅱ, the change was related to the burn surface and depth, but in the group Ⅰ, the change was related to the involvement of body.
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